Irregular sleep patterns linked to harmful bacteria in gut: Research

Wednesday 09th August 2023 06:18 EDT
 

According to recent research, inconsistent sleep habits are connected to dangerous microbes in your gut. A study finds working shifts have been found in previous studies to disturb the biological clock and raise the risk of weight gain, cardiac issues, and diabetes.

Dr. Wendy Hall, a senior author at King's College London, stated, “We know that major disruptions in sleep, such as shift work, can have a profound impact on your health. This is the first study to show that even small differences in sleep timings across the week seems to be linked to differences in gut bacterial species. Some of these associations were linked to dietary differences but our data also indicates that other, as yet unknown, factors may be involved. We need intervention trials to find out whether improving sleep time consistency can lead to beneficial changes in the gut microbiome and related health outcomes.”

In a cohort of 934 people from the ZOE PREDICT study, the largest ongoing nutritional study of its kind, researchers assessed blood, stool and gut microbiome samples as well as glucose measurements in those whose sleep was irregular compared to those with a routine sleep schedule. While previous studies into the association between social jet lag and metabolic risk factors have been done in populations with obesity or diabetes, this cohort consisted of mainly lean and healthy individuals, with most getting more than seven hours of sleep per night throughout the week.

Researchers found that just a 90-minute difference in the timing of the midpoint of sleep – the halfway point between sleep time and wake-up time - is associated with differences in gut microbiome composition. Social jet lag was associated with lower overall diet quality, higher intakes of sugar-sweetened beverages, and lower intakes of fruits and nuts, which may directly influence the abundance of specific microbiota in your gut.

First author Kate Bermingham, Ph.D., from King’s College London and senior nutrition scientist at ZOE, said, “Sleep is a key pillar of health, and this research is particularly timely given the growing interest in circadian rhythms and the gut microbiome. Even a 90-minute difference in the mid-point of sleep can encourage microbiota species which have unfavourable associations with your health.”

Dr. Sarah Berry from King’s College London and chief scientist at ZOE added, “Maintaining regular sleep patterns, so when we go to bed and when we wake each day, is an easily adjustable lifestyle behaviour we can all do, that may impact your health via your gut microbiome for the better.”


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