The University of Birmingham has launched a partnership with Trinity College Dublin to "strengthen European links" amid "post-Brexit uncertainty".
Birmingham says Brexit leaves study opportunities in Europe unclear. But the partnership with Ireland, it says, affords exchange programmes through a "student mobility agreement".
BBC Inside Out West Midlands has been told Birmingham's undergraduate recruitment from EU nations has dropped sharply in recent years. In the event of a no-deal Brexit outcome, a spokesperson told the programme the university could lose tens of millions of pounds.
Birmingham said the partnership would allow collaboration across three research areas: medical schools' clinical trials; bioengineering; and digital textual editing.
In a statement released on Friday, vice-chancellor Sir David Eastwood said: "Europe continues to be a region of key importance.
"As a major strand in our global engagement strategy, we are building and strengthening partnerships with priority institutions across the EU, and are delighted to agree this key partnership with [Trinity College]."